The Third International Symposium on Vascular Tissue Engineering   |   614.355.0650|
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Conference Overview

ISVTE logo-long

On behalf of the organizing committee, it is a great pleasure to announce the Third International Symposium on Vascular Tissue Engineering (ISVTE) that will be held on June 5-6, in Columbus, Ohio at Nationwide Children’s Hospital. The meeting will bring together biologists, engineers as well as clinicians that are active in the field of vascular tissue engineering.

The ISVTE provides state-of-the-art lectures by prominent international vascular tissue engineering scientists. In addition to the invited lectures, researchers from all over the world will present their oral abstracts and posters. The ISVTE will be held in the United States in the capital of the midwestern state of Ohio.

In its third session, this biennial meeting aims to bring together scientists and clinicians that are active in the field of vascular tissue engineering to share current research, best practices and new techniques.

On behalf of the ISVTE organizing committee,
We look forward to welcoming you in Ohio!


ISVTE Objectives

  • Summarize the role of regenerative medicine in treating the anatomical and functional deficits that affect vascular systems
  • Differentiate the benefits and drawbacks of various tissue engineering techniques when applied to distinct vasculature systems and diseases
  • Apply emerging research findings on studies and/or patients with vascular diseases and their treatment
  • Develop basic, translational and clinical collaborations with other physicians and scientists to accelerate progress in the management of patients with vascular diseases
  • Recognize areas in need of further investigation prior to clinical application

Planning Committee

<b>Toshiharu Shinoka, MD</b>
Toshiharu Shinoka, MDCo-Director; Tissue Engineering Program at Nationwide Children’s Hospital
Columbus, Ohio – USA
<b>Christopher Breuer, MD</b>
Christopher Breuer, MDCo-Director; Tissue Engineering Program at Nationwide Children’s Hospital
Columbus, Ohio – USA
<b>Laura Niklason, MD, PhD</b>
Laura Niklason, MD, PhDProfessor of Anesthesiology & Biomedical Engineering at Yale University
New Haven, Connecticut – USA
7:15 – 8:00 AM | Breakfast/Check-In

8:00 – 8:25 AM | Opening Remarks
Toshiharu Shinoka, Christopher Breuer & Laura Niklason

Recent Progress in Scaffolds for TEVG – 1
Chair: Anthony Weiss | Gary Bowlin | Peter Ma

8:30 – 8:55 AM | Designing Scaffold Microenvironments to Direct Blood Vessel Regeneration
Peter Ma

8:55 – 9:20 AM | Elastin as a High Value Component of Tissue Engineered Vessels
Anthony Weiss

9:20 – 9:45 AM | Designing Bioresorbable Vascular Prosthetics to Regulate Outcome Derived from Acute Confrontation with Neutrophils
Gary Bowlin

9:45 – 10:05 AM | Break

Basic Science – 1
Chair: Yasuko Iwakiri | Elena Aikawa

10:05 – 10:25 AM | Hemodynamic Changes and Hepatic Remodeling
Yasuko Iwakiri

10:25 – 10:50 AM | Novel Aspects in Cardiovascular Research
Elena Aikawa

10:50 – 11:10 AM | Pathologic Considerations in Cardiovascular Tissue Engineering
Frederick Schoen

11:10 – 11:30 AM | Computer Model Driven Design of Tissue Engineered Vascular Grafts
J.D. Humphrey

11:30 AM – 12:30 PM | Lunch

12:30 – 1:00 PM | Fung Wexner Lifetime Achievement Award Presentation 

Clinical Needs of Vascular Tissue Engineering

Chair: Toshiharu Shinoka

1:00 – 1:20 PM | Implantation of Tissue Engineered Inferior Vena Cava in a lamb model
Christopher Breuer

1:20 – 1:50 PM | Transcatheter Assessment of TEVG from Catheterization Laboratory in Animal Facility at Nationwide Children’s Hospital
John Cheatham

1:50 – 2:15 PM | Core Matrix Valve Conduit
Patrick McConnell

2:15 – 2:40 PM | Patient Specific Hemodynamics and Growth and Remodeling in Congenital Heart Disease Surgery
Alison Marsden

2:40 – 3:05 PM | Optimizing Vascular Graft Endothelialization by Transmural Ingrowth
Tim Pennel


3:05 – 3:25 PM | Break

Recent Progress in Scaffolds for TEVG – 2

Chair: William Wagner | Xiumei Mo

3:25 – 3:50 PM | Modification of Vascular Grafts with Vasoactive Substances to Improve Blood Vessel Regeneration and Function
Deling Kong

3:50 – 4:15 PM | Nanofibrous Tube Scaffold for Blood Vessel Tissue Engineering
Xiumei Mo

4:15 – 4:40 PM | Polymer Design and Processing for Cardiovascular Applications
William Wagner

4:40 – 5:30 PM | Poster Session

5:30 – 7:00 PM | Reception with Heavy Hors d’Oeuvres & Optional NCH Tour 
Live Music – Stecker Lobby

7:15 – 8:10 AM | Breakfast/Check-In

8:10 – 8:15 AM | Opening Remarks
John Barnard

Current Strategies for Tissue-Engineered Artery
Chair: Joris Rotmans | Yadong Wang

8:15 – 8:40 AM | Contribution of Stem Cells to Vascular Regeneration and Fibrosis
Song Li

8:40 – 9:05 AM | In Situ Tissue Engineering of Blood Vessels
Yadong Wang

9:05 – 9:30 AM | Vascular Tissue Engineering: “Quo Vadis”?
Beat Walpoth

9:30 – 9:55 AM | Human Adipose-Derived Mesenchymal Stem Cell-Based Engineered Vascular Grafts: Practical Considerations for Translation
David Vorp

9:55 – 10:20 AM | Autologous In Vitro Engineered Vascular Grafts for Hemodialysis Access
Joris Rotmans

10:20 – 10:45 AM | Break

Oral Sessions
Chair: Toshiharu Shinoka

10:45 – 11 AM | An Optimized Induced Pluripotent Stem Cell-Derived Tissue Engineered Blood Vessel Model Of Hutchinson-Gilford Progeria Syndrome For Drug Toxicity Testing

11 – 11:15 AM | Adipose-Derived Stem Cells And Vascularized Lymph Node Transfers Successfully Treat Mouse Hindlimb Secondary Lymphedema Through Early Re-Connection Of The Lymphatic System And Lymphangiogenesis

11:15 – 11:30 AM | First clinical application of the human Biotube to the congenital heart disease

11:30 – 11:45 AM | In Vivo Tissue-Engineering of Poly (ε-caprolactone) Reinforced Vascular Grafts

11:45 AM – 12 PM | Excellent Long-Term In-Vivo Data with Bioabsorbable Carotid Grafts

12 – 12:15 PM | Luminal Evolution of the Tissue-Engineered Vascular Graft

12:15 – 1:30 PM | Lunch and Progress Toward a Tissue Engineered Heart Valve John Mayer, Jr. – Fung Wexner Lifetime Achievement Award Recipient

Future Clinical Application of Tissue Engineering Vascular Grafts
Chair: Christopher Breuer | Prabir Roy-Chaudhury

1:30 – 1:55 PM | Completely Biological “Off-the-Shelf” Vascular Grafts
Robert Tranquillo

1:55 – 2:20 PM | Design and Preclinical Validation of Small-Diameter Vascular Grafts
Didier Letourneur

2:20 – 2:45 PM | Vascular Tissue Engineering for Skeletal Muscle Regeneration/Repair
George Christ

2:45 – 3:10 PM | Bioengineered Solutions for Dialysis Vascular Access Dysfunction: Challenging the Status Quo…
Prabir Roy-Chaudhury

3:10 – 3:30 PM | Break

Current Status of Clinical Application of Tissue Engineering Vascular Grafts
Chair: Christopher Breuer | Laura Niklason | Toshiharu Shinoka

3:30 – 3:55 PM | Tissue Engineered Vascular Grafts for Use in Congenital Heart Surgery
Christopher Breuer

3:55 – 4:20 PM | Building completely Biological, Woven, Human Tissue Engineered Blood Vessels
Nicolas L’Heureux

4:20 – 4:45 PM | Long term clinical outcomes of Tissue Engineered Vascular Conduits in Pediatric Cardiovascular Surgery
Toshiharu Shinoka

4:45 – 5:10 PM | Clinical Follow-up of Patients receiving Tissue Engineered Arteriovenous Grafts
Laura Niklason

5:10 – 5:15 PM | Closing Remarks
Laura Niklason

Online registration is now closed.

Speakers & Faculty

<b>Elena Aikawa, MD, PhD</b>
Elena Aikawa, MD, PhDBoston, MA, USA
Brigham and Women’s Hospital, Harvard Medical School
<b>Gary Bowlin, PhD</b>
Gary Bowlin, PhDMemphis, TN, USA
University of Memphis
<b>John Cheatham, MD</b>
John Cheatham, MDColumbus, OH, USA
Nationwide Children's Hospital
<b>George Christ, PhD</b>
George Christ, PhDCharlottesville, VA, USA
University of Virginia
<b>Mark Galantowicz, MD</b>
Mark Galantowicz, MDColumbus, OH, USA
Nationwide Children's Hospital
<b>J.D. Humphrey, PhD</b>
J.D. Humphrey, PhDNew Haven, CT, USA
Yale University
<b>Yasuko Iwakiri, PhD</b>
Yasuko Iwakiri, PhDNew Haven, CT, USA
Yale University
<b>Deling Kong, PhD</b>
Deling Kong, PhDTianjin, China
Nankai University
<b>Didier Letourneur, PhD</b>
Didier Letourneur, PhDParis, France
CNRS - French National Center for Scientific Research
<b>Nicolas L'Heureux, PhD</b>
Nicolas L'Heureux, PhDTalence, France
Inserm - University of Bordeaux
<b>Song Li, PhD</b>
Song Li, PhDLos Angeles, CA, USA
UCLA Engineering
<b>Peter Ma, PhD</b>
Peter Ma, PhDAnn Arbor, MI, USA
University of Michigan
<b>Alison Marsden, PhD, MSE, BSE</b>
Alison Marsden, PhD, MSE, BSEStanford, CA, USA
Standford University
<b>John Mayer Jr., MD</b>
John Mayer Jr., MDBoston, MA, USA
Boston Children’s Hospital & Harvard Medical School
<b>Patrick McConnell, MD</b>
Patrick McConnell, MDColumbus, OH, USA
Nationwide Children's Hospital
<b>Xiumei Mo, PhD</b>
Xiumei Mo, PhD Shanghai, China
Donghua University
<b>Tim Pennel, MBChB, PhD</b>
Tim Pennel, MBChB, PhDCape Town, South Africa
University of Cape Town
<b>Joris Rotmans, PhD</b>
Joris Rotmans, PhDLeiden, Netherlands
Leiden University Medical Center
<b>Prabir Roy-Chaudhury, MD, PhD</b>
Prabir Roy-Chaudhury, MD, PhDTucson, AZ, USA
University of Arizona Health Sciences
<b>Frederick Schoen, MD, PhDi</b>
Frederick Schoen, MD, PhDiBoston, MA, USA
Brigham and Women’s Hospital, Harvard Medical School
<b>Robert Tranquillo, PhD</b>
Robert Tranquillo, PhDMinneapolis, MN, USA
University of Minnesota
<b>David Vorp, PhD</b>
David Vorp, PhDPittsburgh, PA, USA
University of Pittsburgh
<b>William Wagner, PhD</b>
William Wagner, PhDPittsburgh, PA, USA
University of Pittsburgh
<b>Beat Walpoth, MD, PD, FAHA</b>
Beat Walpoth, MD, PD, FAHAGeneva, Switzerland
Geneva University Hospital
<b>Yadong Wang, PhD</b>
Yadong Wang, PhD Pittsburgh, PA, USA
University of Pittsburgh
<b>Anthony Weiss, PhD</b>
Anthony Weiss, PhDSydney, Australia
University of Sydney

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